Abstract Background Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches.The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein.However, the majority of human sarcomas have norma
ENY-838, a 4-page illustrated fact sheet by William H.Kern, Jr., provides useful information for keeping pests out of bird and mammal nest boxes, especially Liquid Lipstick the Africanized honey bee, which has become established in Florida, and sets up colonies in smaller and lower locations which may displace wildlife that uses these locations as
This theoretical work reports the dispersion and absorption characteristics of horizontally polarized shear wave (SH-wave) in a corrugated medium with void pores sandwiched between two dissimilar half-spaces.The dispersion and absorption equations have been derived in a closed form using the method of separation of variables.It has been established